セミナー・シンポジウム Seminars & Symposium

【11/28】第6回AIMRジョイントセミナー

2014年度 第6回AIMRジョイントセミナーのご案内

Title

Microengineering for biomedical applications

Speaker

竹内 昌治 教授
（東京大学生産技術研究所 教授）

Date

2014年11月28日（金） 16:00-17:00

Venue

AIMR本館2階 セミナー室

Abstract

Here, I am planning to talk about several MEMS/Microfluidic-based approaches for various biomedical applications including implantable monitoring and tissue engineering.
Fluorescent hydrogels hold great promise for in vivo continuous glucose monitoring with wireless transdermal transmission and long-lasting activity. We synthesized a highly-sensitive fluorescent monomer, and then fabricated injectable-sized fluorescent polyacrylamide hydrogel beads and fibers with high uniformity and high throughput. We find that the fluorescent beads/fibers provide sufficient intensity to transdermally monitor glucose concentrations in vivo.
Macroscopic 3D tissue architectures are important for not only in tissue engineering but also drug testing. We demonstrated a construction method of 3D tissue structures by using cell beads and cell fibers. For example, a cell-encapsulating core-shell hydrogel fiber was used for constructing fiber-based tissues including muscles, nerves and blood vessels. Moreover, the fiber encapsulating beta-cells is used for the implantation of diabetic mice, and succeeded in normalizing the blood glucose level.

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